DECEMBER 16, 1986 / MONTROSE VOICE 3
AIDS: New Findings May
Show Why Gay Men Victims
By Jan Ziegler
WASHINGTON (UPI)—The AIDS
virus is capable of infecting cells in the
colon and rectum, a finding that may
help explain the high proportion of
AIDS among gay men, researchers said
Dr. Malcolm A. Martin, chief of the
laboratory of molecular microbiology at
the National Institute of Allergy and
Infectious Diseases, said the finding
was unexpected because it was thought
the AIDS virus attacked only lymphocytes and monocytes, both white blood
cells crucial to the body's immune system .
However, the finding may help
explain how the virus is transmitted
during anal intercourse, he said, a technique favored by many gay men and
practiced occasionally by heterosexuals.
"It's thought the reasons gay men
become infected is because there's a lot
of trauma (to rectal tissues)" during
anal intercourse, he said, allowing pas
sage of the virus from semen into the
recipient's bloodstream through minute
But he said the research shows "no
trauma is necessary. Anal intercourse,
whether it's heterosexual or homosexual, might be dangerous to one's
"The big overall picture is maybe the
portal of entry in people who practice
anal intercourse is the colon first. The
virus can be transferred to lymphocytes
and they gain access to the ciruclation.
That's the way you set up this rip-
Once the acquired immune deficiency
syndrome virus attacks cells of the
immune system, in about 30 percent of
cases, resistance to infection is gradually destroyed and the victims fall prey
to a variety of diseases.
Martin and his colleagues did not find
infected colorectal cells in people carrying the AIDS virus. He said that is the
next step in resarch.
What the scientists did was grow the
HOLIDA Y SCHEDULE
To better serve Montrose and the Houston gay community, the Montrose Voice is now
published twice a week (except during certain holiday weeks, including Thanksgiving
1986, Christmas 1986 and New Year's 1986-87, when the Voice will be publishing only once
during the week) Al! editions of the Voice will be free (except through our vending
machines) and will be available through our regular distribution outlets. Also, home
delivery is available in Greater Montrose at $1.25 per week (price is regardless of the
number of issues published during the week).
Issue Release Display Classified Distn- Rate
" Date Deadline Deadline bulion Card
319a Tuesday. Dec. 2 2pm Monday
319b Friday. Dec 5 5pm Wednesday
320a Tuesday. Dec 9 2pm Monday
320b Friday. Dec 12 5pm Wednesday
321a Tuesday, Dec 16 2pm Monday
321b Friday, Dec. 19 5pm Wednesday
322 Wednesday. Dec. 24 2pm Monday
323 Tuesday, Dec. 30 2pm Monday
324a Tuesday. Jan 6 2pm Monday
2pm Monday 5.000 50%
2pm Monday 10.000 100%
2pm Monday 10.000 100%
2pm Monday 5,000 50%
Friday. Jan 9
5pm Wednesday 2pm Thursday 10.000 100%
And every Tuesday and Friday through January
The Montrose Voice
ir EVERY TUESDAY & WEDNESDAY
The Midweek Extra-
News and Ads that Can't Wait til the Weekend
• EVERY FRIDAY
The 'Big Edition'—With the Largest Houston Circulation
of all the Gay Publications
To advertise before our estimated 40,000+
readers each week, call us. We'll help you
convince our readers to be your customers.
Estimated readership figure assumes a pass-on rate factor of 28
cells in culture. Because it is hard to
keep this kind of cell alive in the lab, the
ones Martin's team used were cancerous
and were thus able to continue multiplying.
They found three of the five cell samples from the colon and rectum could be
infected with the AIDS virus, while
none of other types of cells—such as
lung, pancreas and ovary—the scientists studied were susceptible.
The colorectal cells were found to
prouduce the kind of RNA, or genetic
material, that directs production of a
molecule called CD4. This same molecule is found on the surface of the T4
lymphocyte and the other immune
sytem cells known to be attacked by the
"It's very likely if you look hard
enough, if you do studies with fresh normal cells, a simliar thing might occur
with vaginal cells," Martin said.
Scientists have shown AIDS can be
transmitted through normal heterosexual intercourse. It is uncertain how the
virus can be passed from an infected
woman to a man, although scientists
have theorized tiny abrasions on the
penis may permit the virus to enter.
Although some scientists believe the
virus also infects certain cells of the
brain, Martin said his team's finding
that the AIDS virus is carried in monocytes disproves this.
CAMBRIDGE, Mass. (UPI)—Scientists
have used genetic engineering techniques to produce large amounts of a
natural human protein that may be useful in treating cancer and other diseases, the researchers reported last
week, Dec. 8.
The protein, known as macrophage
colony stimulating factor— M-CSF or
CSF-1—stimulates the activity of blood
cells known as macrophages, which are
involved in coordinating the body's
defense against disease.
The substance may one day be used to
strengthen the body's ability to fight
cancers and other diseases by boosting
patients' immune systems, according to
researchers at the Genetics Institute
Inc., a biotechnology firm.
The company has begun testing the
substance in animals and plans to
begin human testing in 1987, officials
Natural M-CSF has been isolated in
small amounts from human urine.
Working with Japanese scientists, the
Genetics Institute team showed that the
genetically engineered substance is
identical to the natural protein, they
The substance is the third blood cell
growth factor developed by the company. The other two are granulocyte
monocyte colony stimulating factor
(GM-CSF) and multi-CSF, which is also
known as interleukin-3.
Scientists are testing those substances and several similar ones for treating
a variety of diseases, including cancer
and diseases of the immune system,
such as AIDS.
Drs. Gordon Wong and Steve Clark of
the Genetics Institute presented their
work with M-CSF at a meeting of the
American Society of Hematology in San
By Mark Orion
For Tuesday evening. Dec 16. through Friday
morning. Dec. 19. 1986
ARIES—So the big, tough guy is going
to let them know just how he really feels,
huh? Anger is real and fine, but don't let
an outburst at the wrong time ruin what
you've so carefully built. Being strong
and being rigid are two different things.
TAURUS—Oh, you kid! You've got this
terrific talent for letting the child in yourself entertain and complement the adult.
Others enjoy this quality in you, especially right now, when you can use it to
bring a sense of play into your work.
GEMINI—Aren't you forgetting something? Sure, you have an appetite for the
unusual, but there are limits. Watch out
for the far out. When something begins to
become an obsession, it's time to take
stock of what you really need and want.
CANCER—That secret affair that
you've been having will beeo much fun
this week that you may be tempted to
bring it out in the open. There's a war
going on in your head. This is the time to
be a general. Avoid being irrational, but
LEO—A weary end of the week can be
avoided if you're able to see that the line
between work and play is not as clear-cut
as you thought. That person who made
you feel so good last weekend could be a
real help in this regard.
VIRGO—Zip, wham, wow, shazam!
Some unexpected energy and desire
comes out of nowhere. Most people
would feel that they were caught in a
whirlwind, but you're able to managejust
fine. A special and exciting time.
LIBRA—The buzz of gossip and whispered innuendoes are flying all around
you. While your ears are burning with all
those crazy sounds, you're concerned
with more important things like loving
what you have and knowing how how
deep that love goes.
SCORPIO—Your friends get high just
being near you, and your lover or other is
•wearing a big smile. Fun and games and
colorful pleasure. Spring is all over the
place, and so are you: dancing, romancing, shining lights in dark places, making
things move, watching them grow.
about the future and where you're going
to be when you get there. You know that
changes are coming up, yet there's that
nagging uncertainty that won't let go A
week to practice patience. It's coming.
Really it is.
CAPRICORN—The rules of the game
are what's important to you this week.
Stategy and moves are what you get
involved in. Be able to bend with a sudden
wind. Think about what would happen if
you got caught with your pants down.
Remember to laugh.
AQUARIUS—Your emthusiasm plus
your ability to share it equals joy. The
ability to be sympathetic without being
patronizing is a real gift. Whatever it is
you've got. there's no way you can avoid
PISCES—Dressing up or dressing
down, wearing a mask or a strange disguise you don't mind. You know what it's
for. You're carrying out last week's plans.
Perhaps you're a spy in the house of love.
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