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Houston Voice, No. 1018, April 28, 2000
File 005
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Houston Voice, No. 1018, April 28, 2000 - File 005. 2000-04-28. University of Houston Libraries. University of Houston Digital Library. Web. October 19, 2019. https://digital.lib.uh.edu/collection/montrose/item/1889/show/1864.

Disclaimer: This is a general citation for reference purposes. Please consult the most recent edition of your style manual for the proper formatting of the type of source you are citing. If the date given in the citation does not match the date on the digital item, use the more accurate date below the digital item.

(2000-04-28). Houston Voice, No. 1018, April 28, 2000 - File 005. Montrose Voice. University of Houston Libraries. Retrieved from https://digital.lib.uh.edu/collection/montrose/item/1889/show/1864

Disclaimer: This is a general citation for reference purposes. Please consult the most recent edition of your style manual for the proper formatting of the type of source you are citing. If the date given in the citation does not match the date on the digital item, use the more accurate date below the digital item.

Houston Voice, No. 1018, April 28, 2000 - File 005, 2000-04-28, Montrose Voice, University of Houston Libraries, accessed October 19, 2019, https://digital.lib.uh.edu/collection/montrose/item/1889/show/1864.

Disclaimer: This is a general citation for reference purposes. Please consult the most recent edition of your style manual for the proper formatting of the type of source you are citing. If the date given in the citation does not match the date on the digital item, use the more accurate date below the digital item.

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Title Houston Voice, No. 1018, April 28, 2000
Contributor
  • Hennie, Matthew A.
Publisher Window Media
Date April 28, 2000
Language English
Subject
  • LGBTQ community
  • LGBTQ people
  • Gay liberation movement
Place
  • Houston, Texas
Genre
  • newspapers
Type
  • Text
Identifier OCLC: 31485329
Collection
  • University of Houston Libraries Special Collections
  • LGBT Research Collection
  • Montrose Voice
Rights In Copyright
Note This item was digitized from materials loaned by the Gulf Coast Archive and Museum (GCAM).
Item Description
Title File 005
Transcript APRIL 28, 2000 • HOUSTON VOICE CRIXIVAN ^^=-=(indinavir sulfate) Patient Information about CRIXIVAN' (KRiK-sih-van) Please read this information before you start taking CRIXIVAN. Also, read the leaflet each time you renew your prescription, just in case anything has changed. Remember, this leaflet does not take trie place of careful discussions with your doctor. You and your doctor should discuss CRIXfVAN when you start taking your medication and at regular checkups. Vou should remain under a doctor's care when using CRIXIVAN and should not change or stop treatment without first talking with your doctor What is CRIXIVAN? CRIXIVAN is an oral capsule used for the treatment of HIV (Human Immunodeficiency Virus). HIV is the virus that causes AIDS (acquired immune deficiency syndrome). CRIXIVAN is a type of HlV drug called a protease (PRO-tee-ase) inhibitor. How does CRIXIVAN work? CRIXIVAN is a protease inhibitor that fights HIV. CRIXIVAN can help reduce your chances of getting illnesses associated with HIV. CRIXIVAN can afso help lower the amount of HIV in your body (called "viral load") and raise youf C04 (T) cell count. CRIXIVAN may not have these effects in all patients. CRIXIVAN is usually prescribed with other anti-HIV drugs such as ZDV (also called AZT), 3TC, ddl, ddC. or d4T. CRIXfVAN works differently from these other anti-HIV drugs. Talk with your doctor about how you should take CRIXIVAN. CRIXIVAN has been studied in adults. The safety and effectiveness of CRIXIVAN in children and adolescents have not been established. How should I take CRIXIVAN? There are six important things you must do to help you benefit from CRIXIVAN: ' Take CMXJVAN capsules every day as prescribed by your doctor. Continue taking CRIXIVAN unless your doctor tets you to stop. Take the exact amount of CHXiVAN that your dot^^ you to lake. start. To help make sure you will benefit from CRIXIVAN. you must not skip doses or take 'drug holidays". If you don't take CRIXIVAN as prescribed, the activity of CRIXIVAN may be reduced (due to resistance). 2 Take CRIXIVAN capsules every 8 hours around the clock, every day. It may be easier to remember to take CRIXIVAN if you take it at the same time every day. if you have questions about when la take CRIXIVAN, your doctor or health care provider can help you decide what schedule works for you 3 If you miss a dose by more than 2 hours, wait and then take the next dose at the regularly scheduled time. However, if you miss a dose by less than 2 hours, take your missed dose immediately. Then take your next dose at the regularly scheduled time. Do nol take more or less man your prescribed dose of CRIXIVAN at any one lime. 4 Take CRIXIVAN with water. Vou can also take CRIXIVAN with other beverages such as sjum or non-fat milk, juice, coffee, or tea. 5. Ideally, take each dose of CRIXIVAN without food but with water at least one hour before or two hours after a meal. Or you can take CRIXIVAN wrth a Ugh] meal. Examples of light meals include: dry toast with jelly, juice, and coffee (with 3gm or non-fat milk and sugar if you want) com flakes with sjjjfn or non-fat milk and sugar Do not take CRIXIVAN at the same time as any meals that are high in calories, fat, and protein (for example — a bacon and egg breakfast). When taken at the same time as CRJXIVAN, these foods can interfere with CRIXIVAN being absorbed into your bloodstream and may lessen its effect. 6 ft is critical that you drink at (east six 8-ounce glasses of liquids (preferably water) throughout the day, every day. CRIXIVAN can cause kidney stones. Having enough fluids in your body should help reduce the chances of forming a kidney stone. Call your doctor or other health care provider if you develop kidney pains (middle to lower stomach or back pain) or blood in the urine. Does CRIXIVAN cure HIV or AIDS? CRKIVAN is not a cure for HIV o«AIDS. People taking CftDQVAN may still develop infections or other conditions associated with HIV. Because of this, it is very important for you to remain under the care of a doctor. Although CRIXIVAN is not a cure for HIV or AIDS, CRIXA/AN can help reduwywr chances of getting illnesses, including death, associated with HIV. CRIXIVAN may not have these effects in all patients. Does CRIXIVAN reduce the risk of passing HlV to others? CRIXIVAN has not been shown to reduce the risk of passing HlV to others through sexual contact or blood contamination Who should not take CRIXIVAN? Do not take CRIXIVAN if you have had a serious allergic reaction to CRIXIVAN or any of its components. What other medical problems or conditions should I discuss with my doctor? Talk to your doctor if: ■ You are pregnant or if you become pregnant while you are taking CRIXIVAN. We do not yet know how CRIXIVAN affects pregnant women or their developing babies. ■ You are breast-feeding. You should stop breast-feeding if you are taking CRIXIVAN. Also talk to your doctor If you have: ■ Problems with your liver, especially if you have mild or moderate liver disease caused by cirrhosis ■ Problems with your kidneys. ■ Diabetes ■ Hemophilia ■ High cholesterol and you are taking cholesterol-lowering medicines called "statins". Tell your doctor about any medicines you are taking or plan to take, including non-prescription medicines. Tins medication was prescribed lor your particular condition. Do not use it lor any other condition or give it to anybody else. Keep CRIXIVAN and all medicines out of the reach of children. If you suspect that more than the prescribed dose ot this medicine has been taken, contact your local poison control center or emergency room immediately. Triis leaflet provides a summary ol tnfor ration about CRIXIVAN If you riave any questions or concerns about either CRKIVAN or HP/, talk to your doctor. Can CRIXIVAN be taken with other medications?'* Drugs you shou!d_nol.ta_k_e with CRIXIVAN: SELDANE* (terfenadine) HISMANAL" (astemizole) VERSED* (midazolam) HALCION* (triazolam) PROPULSID* (cisapride) Ergot medications (e.g., Wigraine* and Cafergot*) Taking CRIXIVAN with the above medications could result in serious or life-threatening problems (such as irregular heartbeat or excessive sleepiness). In addition, you should not take CRIXIVAN with rifampin, known as RIFADIN*. RIFAMATE*, RIFATER"! or RIMACTANE*. Drugs you can take with CRIXIVAN include: RETROVIR* (zidovudine. ZDV also called AZT) ZERIT" (stavudine, d4T) BACTRIM*/SEPTRA" (trimethoprim/sulfamethoxazole) BIAXIN* (clarithromycin) TAGAMET'(cimetidine) VIDEX* (didanosine, ddl) - MYCOBUTIN* (rifabutin) - EPIVIR" (lamivudine, 3TC) isornazid (INH) DIFLUCAN* (fluconazole) 0RTH0-N0VUM 1/35" (oral contraceptive) Methadone - If you take CRIXIVAN with VIDEX*. take them at least one hour apart. - If you take CRiXiVAN with MYCOBUTIN*, your doctor may adjust both the dose of MYCOBUTIN and the dose of CRIXIVAN. NIZORAL* (ketooonazoie) — If you take CRKIVAN with NIZORAL'; your doctor may adjust the dose of CRIXIVAN. RESCRPTOR* (delawdine)—If you take CflMVAN with TtSCRJPTOR*. your doctor may adjust the dose of CRWVAN. SPORIW)? fracona^ SUSTTVA" (efavirenz)—If you take CRIXIVAN with SUSTIVA". your doctor may adjust the dose of CRIXIVAN. Talk to your doctor about any medications you are taking. What are the possible side effects of CRIXIVAN? like all prescription drugs.CRIXIVAN can cause side effects. The following is not a complete list of side effects reported with CRIXfVAN when taken either alone or with other anti-HIV drugs. Do nol rely on this leaflet alone for information about side effects. Your doctor can discuss with you a more complete list of side effects. Some patents treated with CRIXIVAN developed kidney stones. In some of these pahents this led to more severe kidney problems, including kidney failure or inflammation of the kidneys. Drinking at feast six 8-ounce glasses of liquid (preferably water) each day should help reduce the chances of forming a kidney stone. Call your doctor or other health care provider if you develop kidney pains (middle to tower stomach or back pain) or blood in (he urine. Some patients treated with CRIXIVAN have had rapid breakdown of red blood cells (hemolytic anemia) which in some cases was severe or resulted in death. Some patients treated with CRIXIVAN have had liver problems including liver failure and death. Some patients had other illnesses or were taking other drugs. It is uncertain if CRIXIVAN caused these liver problems. Diabetes and high blood sugar (hyperglycemia) have occurred in patients taking protease inhibitors. In some of these patients, this led to ketoacidosis, a serious condition caused by poorly controlled blood sugar. Some patients had diabetes before starting protease inhibitors, olhers did not. Some patients required adjustments to their diabetes medication. Others needed new diabetes medication. In some patients with hemophilia, increased bleeding has been reported. Severe muscle pain and weakness have occurred in patients taking protease inhibitors, including CRIXIVAN, together with some of the cholesterol -lowering medicines called "statins." Call your doctor if you develop severe muscle pain or weakness. Changes in body fat have been seen in some patients taking protease inhibitors. These changes may include increased amount of fat in the upper back and neck ("buffalo hump"), breast, and around the trunk. Loss of fat from the legs and arms may also happen. The cause and long term health effects of these conditions are not known at this time. Clinical Studies Increases in bilirubin (one laboratory test ol liver function) have been reported in approximately 10% of patients. Usually, this finding has not been associated with liver problems, However, on rare occasions, a person may develop yellowing of the skin and/or eyes. Side effects occurring in 2% or more of patients included: abdominal pain, fatigue or weakness, flank pain, feeling unwell, nausea, diarrhea, vomiting, acid regurgitation, loss of appetite, dry mouth, back pain, headache! trouble sleeping, dizziness, taste changes, rash, upper respiratory infection, dry skin, and sore throat. Swollen kidneys due to blocked urine flow occurred rarely. Marketing Experience Other side effects reported since CRIXIVAN has been marketed include: allergic reactions; severe skin reactions: yellowing of the skin and/or eyes; heart problems including heart attack; abdominal swelling; indigestion; inflammation of the kidneys; Inflammation of the pancreas; joint pain; depression; itching; hives; change in skin color; hair loss; ingrown toenails with or without infection; crystals in the urine; painful urination; and numbness of the mouth. Tell your doctor promptly about these or any other unusual symptoms. If Ihe ccfldrtton persists or worsens, seek medicai attention. How should I store CRIXIVAN capsules? ■ Keep CRIXIVAN capsules in the bottle they came in and at room temperature (59°- 86"R ■ Keep CRIXIVAN capsules dry by leaving the small desiccan! "pillow* in the bottle Keep the bottle closed. i i MEKf •> M COPYRIGHT CMERCK 4 CO . he.. 1996 ^999 Al rights reserved. w respectjw M-ners and are not traoamams of U&cki Co. Vk CRIXIVAN" MERCK 003424(31(510)-CflX-C0N Capsules
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